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melanocortin

Melanotan I, Melanotan II and PT-141: the MC1R–MC5R receptor system, pigmentation signaling and central pathways

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Melanocortin Peptides & Receptor Biology

Melanocortin peptides are a family of research compounds that engage the melanocortin receptor system — five G-protein-coupled receptors (MC1R through MC5R) distributed across skin, brain, adrenal, and immune tissue. Because a single receptor family influences pigmentation, energy balance, inflammatory signaling, and central arousal pathways, melanocortin analogues have become valuable tools for probing how one signaling axis produces such diverse biology.

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Mechanism of Action

01

Melanocortin Agonist

Melanotan-2 activates melanocortin receptors throughout the body.

02

Deep Tanning

It strongly stimulates melanin for a fast, deep tan.

03

Curbs Appetite

It can also reduce appetite via melanocortin signaling.

04

Boosts Libido

It enhances sexual arousal and desire.

05

Tan & Vitality

Research shows tanning, appetite control, and libido effects.

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